Sampdoria sacked coach Ciro Ferrara after five months in charge on Monday and replaced him with former Lazio and Palermo boss Delio Rossi following a second straight defeat.
Ferrara, also fired by Juventus after a short spell in 2009/10, has paid the price following the 3-1 defeat at Catania on Sunday which left the Genoa side in 14th place.
"With sadness given the human bonds that have developed, Ciro Ferrara has been relieved of his position," a club statement said.
Much-travelled Rossi, whose best spell as a coach came with Lazio in 2009 when they won the Italian Cup, was last at Fiorentina but left in May after punching his own player Adem Ljajic in the dugout.
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