Since moving to the Stadio Friuli in 2004 the veteran striker has become one of Italy's top marksmen with 184 league goals for the club.
He became one of a select group in November when he notched up the 200th Serie A goal of his career, Di Natale firing Udinese into a lead against Chievo to reach the milestone in what was his 400th league appearance.
His domestic form has earned him 42 Italy caps and plenty of admirers around Europe - including Liverpool and Milan - but he has remained loyal to Udinese.
Such is his commitment to the club, he shelved plans to retire at the end of the 2013-14 campaign for one more year, but as that nears its end Di Natale has announced he will not sign a new deal.
Di Natale is quoted in Tuesday's Gazzetta dello Sport saying: "In June, I will not renew [my contract], I will leave Udinese."
Reports have linked the 37-year-old with a move to the United States after a lucrative offer from an unnamed MLS side, however specific details remain unclear.
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