And having recently despatched Sevilla 4-0 prior to Saturday's 2-2 draw away at Valencia, the former Arsenal talisman is confident Pep Guardiola's side are playing well enough to handle anything Guus Hiddink's side have to throw at them.
"For us it is not a problem that some people have made Barcelona favourites," he said.
"We accept that we will have to fight hard to make sure we make it to the final in Rome. Chelsea boss Guus Hiddink is a great tactician so it will be hard. But if we have enough possession we are capable of destroying any rival we face."
And while all the pre-match hype has centered around Jose Bosingwa's battle with Lionel Messi on the right flank, Henry insists the la Liga leaders have far more in reserve should the Blues be able to negate the diminutive Argentine's threat.
"For me Lionel Messi is without doubt the No.1 player in the world," he said.
"If Leo plays like he has been doing he is capable of sending the Chelsea defenders mad.
"But Barcelona is not all about Messi. Players like Xavi and Iniesta are both unique and brilliant players."
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