With both teams electing not to choose European based players, the Chileans were without Alexis Sanchez, Arturo Vidal and Gary Medal, while the Costa Ricans missed Bryan Ruiz, Alvaro Saborio and Bryan Oviedo.
It only took Chile 13 minutes to get off the mark with Miiko Albornoz underlining the home side's dominance with a crisp strike.
Despite conceding the majority of the possession, Costa Rica managed to hold on to the half-time break but the floodgates opened soon after.
Chilean midfielder Pablo Hernandez struck a quick-fire brace three minutes after half-time to establish a comfortable 3-0 lead for his side.
Any hope of Costa Rica getting back into the game was wiped in the 63rd minute with a second yellow card to defender Michael Umana.
Striker Carlos Munoz finished off the Costa Ricans on 79 minutes as Chile completed a comprehensive victory.
Costa Rica will be hoping to improve when they meet South Korea in a friendly on Friday in the United States, while Chile's next match is a tough exhibition encounter away against Germany.
‘I don’t think Liverpool would look at Ollie Watkins, a striker isn’t a pressing issue for them – it’s Arsenal who need one’ Former Reds star explains why his old club don’t need an out-and-out forward this summer
‘He’ll still be playing at 40 at a good level because he’s in such good shape and looks after himself so well. He does everything to be a top professional’: Ex-Liverpool coach insists Mohamed Salah has plenty more miles in the tank
