Marseille's post-Marcelo Bielsa era began with a loss as Hamari Traore's goal gave Reims a 1-0 victory at the Stade Auguste-Delaune on Sunday.
Bielsa sensationally resigned last week after Marseille's season-opening defeat to Caen and their misery was compounded by Traore's blistering strike 14 minutes in.
Steve Mandanda made a terrific save to deny former Liverpool striker David N'Gog from extending Reims' lead, before the visitors were reduced to 10 men when Jacques-Alaixys Romao recieved a second booking late in the second half.
Elsewhere, PSG made it two wins from as many matches as they saw off Ligue 1 new boys Gazelec Ajaccio with ease at the Parc de Princes.
Quickfire goals from Blaise Matuidi and Thiago Silva early in the first half were enough to seal a 2-0 victory for the champions, though Edinson Cavani missed several golden opportunities to increase the advantage after the interval.
In the day's other fixture, Benjamin Moukandjo's injury-time penalty salavaged a 1-1 draw for Lorient at home to Bastia.
