Jose Mourinho highlighted his prioritisation of the Europa League as Manchester United made eight changes from the Celta Vigo win for Sunday's trip to Arsenal, including handing a first start to Axel Tuanzebe.
Nineteen-year-old Tuanzebe is highly rated by United but his only previous first-team appearance came in a 22-minute cameo against Wigan Athletic in the FA Cup in January.
The DR Congo-born defender was earmarked by Mourinho for potential first-team inclusion during pre-season, and with the coach seemingly favouring United's chances of Champions League qualification via the Europa League over their Premier League placing, he will get the chance to impress for the first time in the top flight.
Usually a centre-half, Tuanzebe will fill in at right-back in a much-changed defensive unit, with Phil Jones, Chris Smalling and David De Gea all fresh after not featuring in Vigo on Thursday.
Captain Wayne Rooney also returns, as do Michael Carrick, Anthony Martial and Juan Mata, with the latter starting for the first time since picking up a groin injury on March 19.
Whereas United are somewhat under strength, Arsenal have named arguably their strongest XI, with Mesut Ozil, Alexis Sanchez and former Old Trafford favourite Danny Welbeck all starting.
Here is how will line up today... May 7, 2017
'People will remember us because we got to No.1 in the world rankings and achieved great things - but our biggest regret is that we didn’t win anything': Ex-Everton star Kevin Mirallas opens up on 'honour' of being part of nation's golden generation
‘I’m sure we’d have finished in the top four or five if he hadn’t joined Chelsea in January. Him leaving damaged the team, but we couldn’t stand in his way’: Alan Curbishley reflects on failed Champions League dream after selling key player
