Leaders Inter Milan look set to be without Samuel Eto'o for Sunday's trip to Livorno after the Cameroon striker suffered another foot injury in Thursday's 5-3 win over Palermo.
"I feel pain," Eto'o told reporters, adding he should be fit for next week's Champions League trip to Dynamo Kiev.
Fellow forward Mario Balotelli also came off against Palermo after an allergic reaction to medicine for a fever while playmaker Wesley Sneijder remains injured.
Faltering AS Roma have Rodrigo Taddei, Daniele De Rossi and Marco Cassetti suspended for Sunday's home game with Bologna while striker Francesco Totti is still out after minor knee surgery.
Club president Rosella Sensi told a shareholders' meeting late on Thursday that she would not quit despite supporter unrest after two failed takeovers and a perceived lack of investment in the close season.
Lazio, like city rivals Roma, have gone on a team-building retreat ahead of Sunday's game at bottom side Siena with coach Davide Ballardini increasingly under pressure.
Media reports have said the club is lining up potential replacements with former Bologna boss and Lazio player Sinisa Mihajlovic seen as a candidate. Ballardini's cause is not helped by midfielder Matuzalem being suspended.
Siena will be under new coach Marco Baroni for the first time after Marco Giampaolo's sacking on Thursday.
"The first enemy to battle against is fear," Baroni told reporters. "But this group has good quality and we've got to react straight away."
AC Milan defender Alessandro Nesta is likely to miss Saturday's home game with high-flying Parma because of a hamstring problem while midfielder Ignazio Abate is suspended.
Juventus are still without strikers Alessandro Del Piero and Vincenzo Iaquinta for Saturday's visit of in-form Napoli so coach Ciro Ferrara may again go with one up front following the 5-1 thrashing of Sampdoria on Wednesday.
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