Second-placed PSG, one point behind leaders Olympique Lyon, could go top if they beat Marseille and the seven-times champions fail to win against Auxerre earlier on Sunday.
Marseille are four points off the pace and will cast their minds back to late October when they missed the chance to lead the standings after losing 4-2 at home to PSG, their first league defeat of the season.
"The whole city expects us to win (in Paris) and it is even more important this time as the stakes are very high again," Marseille captain Lorik Cana told reporters.
PSG, who last won the Ligue 1 title in 1994, have won six out of their seven last league games to reel in Lyon, who are seeking an eighth successive league crown.
"We must be cautious because games follow on very quickly and there is no time to get some rest," PSG coach Paul Le Guen told reporters.
PSG will be without suspended playmaker Stephane Sessegnon against Marseille.
Lyon were knocked out of the Champions League by Barcelona on Wednesday and must quickly regain their focus.
"We have to get over our disappointment and recover from this defeat if we are to successfully defend our title but it is going to be difficult," coach Claude Puel told reporters.
